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However, in line with the specificity of CPA, the C-terminal residues of the L585I, L585M, and L585V variants were cleaved in vitro upon exposure to the enzyme for 5 hours at 37 C, as confirmed by liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis of the C-terminal peptides (Supplementary Table 1)

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Gasotransmitters in cancer: from pathophysiology to experimental therapy

New research is showing they're as influential and their means of action is through the endocannabinoid system: Therefore, astrocytes respond to endocannabinoids that then potentiate the synaptic transmission, indicating that astrocytes are actively involved in brain physiology

These five patients reported good (n = 2), reasonable good (n = 2) or moderate (n = 1) improvement

Chem Biol Interact 1998;24;111-112:1-14