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In the current study, depriving RPE cells of the essential GSH precursor Cys 2 by culturing cells in Cys 2 -free culture medium or blocking de novo synthesis of GSH by using GCL inhibitor BSO or blocking Cys 2 uptake by pharmaceutical inhibition of system x c caused cell death

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The volcano diagram results suggested that PRMT1 was significantly upregulated at both the protein and mRNA levels in the Gly group compared to that of the negative control group (Fig

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These include eyelid edema, conjunctival congestion, corneal abrasions, optic neuropathy, ptosis, purulent ocular secretions, conjunctival and episcleral hyperemia, symblepharon, macular retinal striae, ciliary congestion, corneal edema with Descemets membrane folding, and even vision loss