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Nicotinamide Adenine Dinucleotide (NAD) is a coenzyme that occurs in many living cells and functions as an electron acceptor

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It supports its use in the clinical management of patients with painful diabetic neuropathy, especially in treatment-refractory patients

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It belongs to a broader class of peptide therapeutics that are reshaping how longevity medicine thinks about tissue maintenance, cellular signaling, and the biology of repair

But despite increasing pressure from the FDA to publish results, and despite the obligation on researchers to publish within a year (requirement in force since 2017), many companies still do not publish and the FDA still does not appear to be issuing any fines