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Critical for Pregnancy and Fetal Health Used in prenatal and periconceptional care for high-risk pregnancies or those unable to use oral folic acid

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Physicians switch patients from one to the other without fully explaining why

Alternatively, ibuprofen (200-400 mg every 6-8 hours with food, not exceeding 1200 mg daily for OTC use) can provide both pain relief and anti-inflammatory effects

However, a meta-analysis of four randomized controlled trials was not able to show this treatment was more effective than placebo