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The report focuses on the evidence in three populations, namely the full claimed indication and two subsets of patients with a BRAF mutation

This is catastrophic for research

Cold sensitivity is not listed as a direct adverse effect in FDA prescribing information, but patients commonly report it as an indirect consequence of significant weight loss

None of them are good

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The capsule form can be described as a solution that favours the standardisation of portions of test material and the ordering of laboratory procedures