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We are finalizing our proposal with modifications

Considering the reduced biosynthetic capacity of erythrocytes, they accumulate oxidative changes along their life span and, therefore, the OS-induced changes in RBCs could be used as useful biomarkers in several pathological and physiological conditions

Pathophysiology of acute pancreatitis

The same dynamism applies to immune cells, whose own metabolic reprogramming and vulnerability to ferroptosis are dictated by the local nutrient and redox environment shaped by the entire cellular community

Clinical studies confirm that chronic treatment with AOD9604 showed no adverse effect on insulin sensitivity, making it a metabolically selective approach to body composition optimization under medical supervision

The mechanism underlying this flare-up could be possibly attributed to the molecular mimicry or non-specific adjuvant effect