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The successful wet-laboratory experiment was thus the proof of concept of the model (Gajdanowicz et al., Reference Gajdanowicz, Michard, Sandmann, Rocha, Corra, Ramrez-Aguilar, Gomez-Porras, Gonzlez, Thibaud, van Dongen and Dreyer2011

Notably, we have demonstrated NAC to be efficacious in reducing the sequelae of mTBI in a randomized, double-blind, placebo-controlled study examining mTBI after blast injury [37]

Dietary restriction differentially protects from neurodegeneration in animal models of excitotoxicity

Autophagy 14:20832103

Many patients experience moderate to severe pain, often described as stabbing or burning, which can persist for years after treatment cessation, significantly impairing their quality of life (Michalova et al., 2023

Moreover, a randomized double-blind placebo-controlled clinical trial indicated that supplementation with Coenzyme Q10 (30 mg/day) and L-carnitine (500 mg/day) for 8 weeks had beneficial effects on migraine symptoms and serum levels of lactate (166)