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This review summarizes recent advances in the mechanisms, prevention, and treatment of diabetic complications, alongside a critical examination of current bottlenecks in translational applications

Stability of NAD Metabolites in Blood in vitro The stability of NAD metabolites and glutathiones was assessed in whole fresh blood samples under varying storage temperature and time

Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1

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Syahrir M, Andayani YD, Djamaludin N, Maksudin ES, Muharramah PF, Rosyidi KM, Haddani H, Bahar E

While the largest percentage of intracellular iron is tightly bound to or incorporated into proteins as a cofactor or for storage, small portion of intracellular iron resides in the cytosol and intracellular organelles (e.g., lysosomes) and constitutes a redox-active liable iron pool, which regulates programmed cell death including ferroptosis 42