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showed dietary curcumin prevents LPS-induced neuroinflammation and cognitive impairment in rats by modulating JNK/NF-B/Akt signaling (Khan et al., 2019)

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Such observation is presumably due to the absence of two important processes, the ATP-forming deiminations and proton-motive force generating amino acid decarboxylations, which contribute to energy generation using amino acids in other LAB

However, current research still faces limitations, particularly in elucidating the specific molecular mechanisms and assessing the long-term safety of IF