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This therapy can be beneficial for patients who are unable to obtain sufficient amounts of this nutrient through dietary sources or oral supplements

et al, High prevalence of hyper-homocysteinemia due to marginal deficiency of cobalamin or folate in chronic myeloproliferative disorders

The small molecule inhibitor of Keap-Nrf2 proteinprotein interaction, CPUY192018, has been found to exhibit cytoprotective properties against DSS in both NCM460 cells and mouse colon

As a highly specific ferroptosis inhibitor, Fer-1 surpasses phenolic antioxidants in its ability to suppress ferroptosis, particularly by inhibiting lipid ROS accumulation induced by erastin or RSL3 in HT-1080 human fibrosarcoma cells) (27)

Mitochondrial damage and activation of the STING pathway lead to renal inflammation and fibrosis

Although the curative ratio is comparatively satisfying for early-stage EOC (stage I/II), 75% of patients got diagnosed at stage III/IV due to the non-obviousness and non-typicalness of its incipient symptoms and the lack of effective early detection techniques [6]