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In contrast the findings for glutamine were inconsistent with two studies reporting no significant difference in serum glutamine in children with autistic disorder compared with controls [69, 89], a later study reporting a significant decrease in platelet glutamine in children with autistic disorder [68] and further studies that reported serum glutamate to be significantly higher in adults with autistic disorder [75] and children with autism spectrum disorders (mixed diagnoses) than controls [87]

It also plays a key role in the synthesis of vitamins, including vitamins K and B12 (153)

Effects of micronutritional status on other patient related parameters such as quality of life still have to be evaluated

Over time, eliminating in-office injections may also reduce costs

Cross-linking changes compound these problems

Cureoglu S, Baylan MY, Paparella MM