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Swindell, University of Michigan, USA Copyright 2014 Ables, Brown-Borg, Buffenstein, Church, Elshorbagy, Gladyshev, Huang, Miller, Mitchell, Richie, Rogina, Stipanuk, Orentreich and Orentreich

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5 Chronic inflammation due to gut microbial disorders contributes to Mets Gut microbes play a key role in maintaining physiological functions as they regulate host nutrition, energy harvesting, epithelial homeostasis, immune system, and drug metabolism while maintaining homeostasis ( Figure 3 )