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The in vivo experiments utilized a nude mice xenotransplantation model, while the in vitro investigations employed two breast cancer cell lines, MDA-MB-231 and MDA-MB-468

Literature indicates that the release of damage-associated molecular patterns (DAMPs) in the tumor microenvironment and the activation of immune responses triggered by ferroptosis are important influencing factors for the dual role of ferroptosis (Chen et al

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As the isoforms present in number of classes the purification of a particular isoform for characterization is a challenging task

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