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Ineffective erythropoiesis, peripheral hemolysis and iron overload are important factors responsible for the clinical manifestation of this disease 2,3

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Baba SK, Alblooshi SSE, Yaqoob R, Behl S, Al Saleem M, Rakha EA, Malik F, Singh M, Macha MA, Akhtar MK, Houry WA, Bhat AA, Al Menhali A, Zheng ZM, Mirza S