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The most common adverse reactions (incidence 20%) of pemetrexed, when administered in combination with pembrolizumab and platinum chemotherapy, are fatigue/asthenia, nausea, constipation, diarrhea, decreased appetite, rash, vomiting, cough, dyspnea, and pyrexia

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Thanks to the Vegan Society for allowing us to link to their website: Devalia V et al (2014) Guidelines for the diagnosis and treatment of cobalamin and folate disorders [Accessed 29.11.19] Linnebank et al (2011) Antiepileptic drugs interact with folate and vitamin B12 serum levels [Accessed 22.10.19] Sukumar and Saravanan (2019) Investigating Vitamin B12 deficiency [Accessed 29.11.19]