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The dose escalation design tested different starting doses (2 mg vs 4 mg) to evaluate tolerability

It also plays a role in maintaining nerve cells and constructing DNA

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Studies show that approximately 1% of a high-dose B12 supplement is absorbed through passive diffusion along the entire gastrointestinal tract, completely bypassing the need for Intrinsic Factor or perfect stomach acid levels

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Ensuring adequate vitamin intake of both B12 and D is a great way to keep your energy levels steady