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The true prevalence of PANS/PANDAS is unknown, and estimates vary greatly

Kaempferol inhibits multiple pathways involved in the secretion of inflammatory mediators from LPS-induced rat intestinal microvascular endothelial cells

elevated levels of YAP1 are considered to activate CAFs, resulting in the stiffening of the ECM and the progression of the tumor (96)

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Thus we propose that along with clinical examination, estimation of oxidative stress may serve as supportive additional biochemical markers for early diagnosis and therapeutic intervention