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Byrd-Bredbenner C, Moe G, Beshgetoor D, Berning J

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Antibody dependent cell mediated cytotoxicity is the primary mechanism of action of Inebilizumab which is currently undergoing phase 3 clinical studies in MG (NCT04524273)

Injection of CVF triggers a systemic complement activation that induces acute inflammation response, followed by changes in lung function and morphology