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Additionally, research professionals have demonstrated that DSIP administration can influence the release of pituitary hormones, such as adrenocorticotropic hormone (ACTH) and luteinizing hormone, both of which play a critical role in the stress response and regulating metabolism

found a targetable method for M1-like to M2-like repolarization via clearance of cell-free DNA in RA treatment 46

Cell 9 , 10311044 (2002)

However, some scholars have proposed that the effect of GLP-1 in the liver is indirectly mediated by multiple mechanisms, such as reducing fat absorption or inhibiting fat cells through acyl-CoA synthetase long chain family member 1 (ACSL1), CCAAT/enhancer binding protein (C/EBP), peroxisome proliferator-activated receptor- (PPAR), and sterol regulatory element binding protein-1c (SREBP-1c) pathways to achieve the purpose of reducing liver lipids [38]

10.1016/j.smim.2013.05.006 Semin Immunol

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