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, which involved healthy test subjects aged 21-61 and followed a randomized, placebo-controlled, double-blind, ascending dose design [16]

Community Insights Self-reported by pep-pedia.org users and published research summaries

coli [199]

Amino acid conjugation

Crucially, in an LPS-induced mouse model of acute lung injury, treatment with compound 25L significantly alleviated pulmonary inflammatory infiltration and levels of pro-inflammatory cytokines (IL-1, IL-6, TNF-), providing direct pharmacological evidence supporting the hypothesis that P2Y14R inhibition alleviates lung inflammation (Ma et al., 2025)