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2003;285(5):R9928

Our bodies can store this vitamin in the liver for a long time, so it might take a few years for a deficiency to develop

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AOD-9604 is a synthetic peptide fragment (amino acids 177-191) of human growth hormone, developed to retain fat-metabolizing properties without the broader hormonal effects of full-length hGH

A 12-week randomized trial demonstrated: Average weight loss of 2.6 kg in AOD-9604 group (1 mg/day) versus 0.8 kg in placebo group Preferential reduction in abdominal and visceral fat deposits No adverse effects on carbohydrate metabolism or insulin sensitivity Non-dose-dependent effects, with higher doses (10 mg/day) producing less weight loss than lower doses However, a subsequent 24-week Phase III trial with 502 subjects incorporating intensive diet and exercise showed no statistically significant weight loss compared to placebo, leading to development termination in 2007

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