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Metal-based drugs and imaging agents where the central metal ion is usually the key feature of the mechanism of action

Another possible way in which G6PD-d may affect immune cells is through altering redox homeostasis

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Methylsulfonylmethane inhibits cortisol-induced stress through p53-mediated SDHA/HPRT1 expression in racehorse skeletal muscle cells: A primary step against exercise stress

[2] This is the highest tier of evidence in this entire comparison: randomized, blinded, placebo-controlled, with a hard imaging endpoint (visceral fat measured by CT), replicated across two trials, and reviewed by a regulator

doi: 10.1038/s41577-022-00684-6 146 TaoS.DuanR.XuT.HongJ.GuW.LinA.et al