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We will analyze their targets in IBD pathophysiology, with particular emphasis on delivery strategies

Figure 6 3.8 CB-839 did not improve cytotoxicity in combination with venetoclax, AZD-5991, and ibrutinib in primary CLL lymphocytes We then tested these drug combinations in the primary CLL cells, both in the native condition ( Figure 7A ) and in media supplemented with cytokines (CD40 ligand and interleukin-4) to mimic the microenvironment and maintain viability ( Figure 7B )

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Injectable subcutaneous administration distributes systemically through the bloodstream, reaching skin from the inside while also affecting other tissues

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