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To estimate the effect of the P72R variant on inflammatory signalling, we overexpressed the P72 or R72 variant of TP53 in p53 KO C3H10T1/2 adipocytes, before challenging the cells with 24 h of starvation (Supplementary Fig

PLoS One 6, e28668

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Br J Nutr 83: 5936 pmid:10911766 8

This timeline aligns with the natural turnover of skin cells, which takes about a month for each new layer of skin to reach the surface

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