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Pathologically, infiltration of inflammatory cells contributes to release of inflammatory mediators, including histamine and leukotrienes from mast cells leading to increased vascular permeability, pulmonary oedema, smooth muscle hypertrophy and hyperplasia of mucus producing cells (mucus hypersecretion) (Fireman, 2003)

Zvejniece L, Svalbe B, Vavers E, Ozola M, Grinberga S, Gukalova B, et al

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Nat Med 2024

Small, irregular, spherical, smooth, and non-agglomerated SiNPs with a peak absorbance of 400 nm were synthesized from Pycreus polystachyos

Cagrilintide is a long-acting synthetic analogue of the pancreatic hormone amylin, engineered with a fatty-acid side chain that extends its plasma half-life relative to native amylin