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While sound theoretical rationale exists and multiple acute study designs provide supportive evidence, it is currently unclear whether following this strategy would lead to greater training adaptations and/or whether EAA supplementation would be better than simply ingesting carbohydrate and a quality protein following exercise

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Viral supernatants were collected 48 and 72 h post-transfection, filtered through 0.45 m filters (Millipore, SLHV033RS)

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Furthermore, reduced SNCA protein level by CRISPR-dCas9-DNMT3A system rescued disease-related cellular phenotypic features of SNCA triplicated dopaminergic neurons, such as mitochondrial ROS production and low cell viability (Wllner et al., 2016)