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In the specific in vitro assay measuring synaptogenesis promotion, Dihexa showed activity at picomolar concentrations far lower than concentrations needed for BDNF or other neurotrophic factors to produce comparable effects

Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients

Delayed height gain, underweight status, delayed puberty, and hormonal imbalances are commonly observed in untreated or poorly managed cases

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Trauma may be caused due to vigorous sexual activity or injuries from sports or accidents