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Copper-coordination and ROS generation are flexible with regard to the spacing of these two histidine residues suggesting that physiologically relevant Cubinding motifs are degenerate

[22] successfully isolated a polyprenylated xanthone structurally related to GA from gamboge resin, termed gambogenic acid (GNA

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Frontiers in Pharmacology, 11, 656

Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses

leads to pancreatic islet cell damage, whereas the db/db mouse model is deficient in leptin receptors