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Cold diethyl ether (Et 2 O, 5 mL) was added to the filtered resin followed by centrifugation for 10 min in order to precipitate and collect the crude peptide

(telomerase)Cell-culture work reporting telomerase induction and telomere elongation by the AEDG peptide

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In 1999 he was recruited to Harvard Medical School where his laboratorys research has focused primarily on understanding the role of sirtuins in disease and aging, with associated interests in chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, and cancer

The deregulation of these genes along with other metabolism deregulation resulted in increased oxidative stress hence resulting in unrepairable DNA damage and reduced survival in glioma patients