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Spesolimab was evaluated in a phase I study involving healthy Chinese subjects

Guideline Statements DIAGNOSIS Guideline Statement 1 The basic assessment should include a careful history, physical examination, and laboratory examination to document symptoms and signs that characterize IC/BPS and exclude other disorders that could be the cause of the patient's symptoms

Pluskal, T., Ueno, M

The current biomarkers related to ferroptosis used in preclinical studies are nonspecific, such as GPX4 and ferritin[21, 33], which exist in other cell death modes and certain pathological conditions

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Assessment of the influence of direct tobacco smoke on infection and active TB management