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The optimized nanoparticles improved drug brain permeation, protected dopaminergic cells from toxin-induced damage, and modulated key signaling pathways by upregulating neuroprotective proteins and downregulating neurodegenerative markers, such as -synuclein and phosphorylated tau (149)

By harnessing the therapeutic potential of vitamin B5 and vitamin U, we can strive towards optimizing the management of inflammatory and erosive gastrointestinal diseases and improving patient outcomes

In another study, DCA administration rescued locomotor deficits and elevated PDH activity in mice with ME/CFS-like manifestations induced by a 25-day repeated forced swimming test [145]

The detection limit in artificial urine was determined as 1.6 M, which is 16 more sensitive than commercial dipstick reflectance analyzers such as Urisys 1100 and Clinitek Status+

Thus, both vitamins are essential in DNA, RNA, and protein synthesis as the main structure and functional cellular compounds

Abstract Ferroptosis, a recently identified and iron-dependent cell death, differs from other cell death such as apoptosis, necroptosis, pyroptosis, and autophagy-dependent cell death