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For example, during chronic exposure to alcohol, the glutamatergic system becomes upregulated, leaving the brain exposed to excessive glutamatergic activity when alcohol is abruptly withdrawn

These routines can lead to dehydration, fatigue, and nutrient depletion

doi: 10.1186/s12906-017-1855-4 78 KimM

[PUBMED Abstract] Shago M, Abla O, Hitzler J, et al.: Frequency and outcome of pediatric acute lymphoblastic leukemia with ZNF384 gene rearrangements including a novel translocation resulting in an ARID1B/ZNF384 gene fusion

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AtGLRs participate in key physiological signalling pathways and possess conserved ligand-binding domains, reinforcing their evolutionary connection to animal iGluRs