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Nat Rev Drug Discov 9(5):387398 Clavaguera F, Bolmont T, Crowther RA, et al

Additionally, high levels of expression of Nrf2, ABCC1, ABCC3 plus NAD(P)H dehydrogenase quinone-1 in breast tumors of patients at the time of diagnosis were prognostic of poor survival after tamoxifen therapy

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Based on current data, insufficient engraftment is likely a key reason for the lack of benefit in transplanted patients

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