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The following were extracted from clinical records: demographics, anthropometrical measurements, body mass index (BMI), (classified by the World Health Organization (WHO)), [21] clinical diagnosis based on the patient's profile when admitted to the ICU (chronic liver disease, colorectal cancer (CRC), hepatobiliary cancer, chronic kidney disease (CKD) and other diagnoses), primary reason for admission to the ICU (medical or surgical), acute physiology and chronic health evaluation (APACHE) II score on admission and SOFA scores on admission and day 7, duration of ICU and hospital stay, need for organ support (ventilation, vasopressors or inotrope agents and haemodialysis) and mortality outcome

Collin, B., Busseuil, D., Zeller, M., Perrin, C., Barthez, O., Duvillard, L., et al

Jahn B, Arvandi M, Rochau U, Fiegl H, Goebel G, Marth C, et al

Packaging requirements : While vitamin and mineral supplements remain stable for months or years in simple bottles, hydrogen water requires specialized packaging with hydrogen-retaining materials and minimal headspace to prevent gas escape

M., Poscia, A., Franceschi, F., Delogu, G., Sanguinetti, M., Spirito, M

Key Considerations: Natural Presence in Breast Milk : Glutathione is found in low levels in breast milk and is essential for the developing infant