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Unfortunately, factors like aging, poor nutrition, and environmental stressors can deplete glutathione levels, making the skin more susceptible to dullness and uneven tone

Berberine has also been shown to enhance the expression of a specific enzyme that helps regulate the storage of fat

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This may be partly explained by the MCT4 expression as a major exporter of lactate, which showed higher expression levels on the tumour epithelium compared to the stroma (positive cell counts in medial and lateral tumour regions respectively - epithelium: 77% and 94%

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