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The mechanism underlying RIRI involves an initial phase of acute hypoxia (ischemia) caused by blood flow interruption, followed by a second phase of reperfusion injury when blood flow is restored, which exacerbates tissue damage

Ren Z, Chen X, Hong L, et al

Glucocorticoids (i.e., dexamethasone) can be given in cases of acute asthma exacerbations where a patient does not show sustained improvement or worsens after one bronchodilator, or has a history of severe or recurrent exacerbations

Subtyping of mild cognitive impairment using a deep learning model based on brain atrophy patterns

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In conclusion, hypoxic stress induced autophagy in gills, whereas glutathione attenuated autophagy