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Nearly 20 agents and extracts, including iron chelators and transporter, antioxidants, pharmacodynamic element from traditional Chinese medicine (TCM), ferroptosis-related protein inhibitors, and neuroprotective agent that inhibit ferroptosis have been reported to have a remissioning effect on retinal disease in animal models (Table 2

Recent studies have validated this general approach demonstrating that molecules designed around angiotensin IV or the hinge sequence itself can bind HGF, block its dimerization, and attenuate HGF-dependent cellular actions

K.SchousboeA.WaagepetersenH

Ecotoxicol Environ Saf 236:113493

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The supernatant was reacted with 10 mM acid ninhydrin solution dissolved in 80% ethanol and 0.2 mM citrate buffer (pH 5.0) using the diluent solution (water: n-propanol = 1:1)