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He et al.s PBPK model predicted that schisantherin A from Wuzhi capsules exhibited TDI of CYP3A4, while schisantherin B exhibited both RI and TDI of CYP3A4 and CYP3A5

Role of ferroptosis in AD The regulation of ferroptosis can impact AD through multiple mechanisms, including the regulation of GSH levels, the Fenton reaction, amyloid- (A), lipid metabolism, iron metabolism and the NRF2 signaling pathway (Fig

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However, although beta-carotene is thought to be less hazardous, it also can cause toxic effects in the livers of patients who continue to use alcohol (Leo et al