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Functional studies revealed that PLSCR1 knockdown resensitizes resistant cells to epirubicin, whereas its overexpression exacerbates resistance both in vitro and in vivo

Furthermore, emerging research has elucidated the significance of interaction between lactyl-CoA synthetase and lactyltransferase within the nucleus, which can facilitate the lactylation of histone H3 at lysine 18 (H3K18), such as ACSS2 and KAT2A, as well as GTPSCS and p300

Thymoquinone attenuates oxidative stress of kidney mitochondria and exerts nephroprotective effects in oxonic acid-induced hyperuricemia rats

Briefly, plates were coated overnight with anti-human Fc (Jackson ImmunoResearch Laboratories 109-001-008), blocked for 2 h with PBS 2% BSA at RT, and incubated overnight at 4 C with recombinant Gp1-Fc protein derived from HEK293 cells transfected with LCMV glycoprotein vector

Bisdemethoxycurcumin, a novel potent polyphenolic compound, effectively inhibits the formation of amyloid aggregates in ALS-associated hSOD1 mutant (L38R)

Gen Appl Plant Physiol 31:105124 Edwards R, Blount JW, Dixon RA (1991) Glutathione and elicitation of the phytoalexin response in legume cell cultures