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When severed nerves in animal models were placed in collagen tubes impregnated with GHK, researchers observed significantly increased nerve outgrowth, elevated production of nerve growth factor (NGF) and neurotrophins NT-3 and NT-4, accelerated regeneration of nerve fibers, and increased axon count and Schwann cell proliferation compared to controls

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Interestingly, only a small part of cells expressing low level of GPNMB, were eliminated by the vaccinated mice 62

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