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Sodium phosphate is contraindicated in diseases where high phosphate or low calcium levels may be encountered, and in patients with hypernatremia

10.1183/13993003.00164-2019 74 SderbergD.SegelmarkM

Hammers DW, Merscham-Banda M, Hsiao JY, Engst S, Hartman JJ, Sweeney HL

( R )-2-Amino-3-(3-chlorophenyl)-1-(4-(1-methyl-[1,2,4]triazolo[4,3-a]quinolin-7-yl) piperazin-1-yl)propan-1-one hydrochloride (9i) Yield: 54 mg (77%)

Phase 2 clinical trial data published in the New England Journal of Medicine showed up to 24.2% body weight reduction at 48 weeks the highest ever reported in any obesity clinical trial