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Polyphenols may also help reduce skin inflammation by blocking inflammatory pathways that can lead to skin swelling, discoloration, and dryness

Clinical Uses Hypertension first-line therapy Heart failure improves survival and symptoms Post-myocardial infarction prevents remodeling Diabetic nephropathy / proteinuric kidney disease renal protection Chronic kidney disease slows progression 5

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Additionally, -syn oligomers suppress the lysosomal-mediated degradation of FTN (ferritinophagy), resulting in the disruption of FTN turnover and further contributing to iron accumulation (Xiao et al., 2018)

Antioxidants such as vitamin E, N-acetylcysteine (NAC), and melatonin have been investigated as adjunctive treatments for schizophrenia, where they can reduce oxidative stress damage and improve patients symptoms ( Summary The etiology of schizophrenia has not yet been clarified, and more and more studies have shown that schizophrenia is a progressive neurodevelopmental disorder, and multiple factors play a role in the onset and development of the disease