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doi: 10.1084/jem.20102049 42 HanadaYIshiharaNWangLOteraHIshiharaTKoshibaTet al

Clin Pharmacol Ther 2003

These molecules are linked to the prevention of diseases caused by OS

Our findings suggest that irisin activates the SIRT1 signaling pathway, which is not exclusive to dopaminergic neurons and may also modulate glial function, as evidenced by reduced microglial activation