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Numerous in vitro studies show that ITCs induce apoptosis via both intrinsic and extrinsic pathways (108)for instance, through caspase activation (109), mitochondrial dysfunction (110), and oxidative stress generation (111)

Consequently, future research should focus on identifying precise therapeutic targets and characterizing the alterations in downstream signaling pathways, enabling berberine to exert a pivotal role in the treatment of DN by targeting these pathways

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Bacteriol 186, 244247

Helps protect skin and body cells from environmental stressors like UV rays, pollution, and lifestyle factors that accelerate aging