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Circulation 143 , 11571172 (2021)

However, many studies have emphasized the preventive and therapeutic approaches of antioxidants for patients with DE (Table 4 and Table 5)

Though classically known to participate in the reduction of a broad spectrum of carbonyl-containing substrates including prostaglandins, steroids, and xenobiotics in phase 1 detoxification, a report in 2008 by Bateman et al

Acknowledgements We thank Professor Qianfei Wang (Beijing Institute of genomics, Chinese Academy of Sciences) and Professor Qianben Wang (Department of Pathology, Duke University School of Medicine, Durham, USA) for critical comments and advice on the manuscript

Inhibition of cytochrome P450 enzymes by rhein in rat liver microsomes

Cell 38 (5), 689699