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Furthermore, microbiota composition varies depending on its localization in the gastrointestinal system

The rapid activation and resolution of immune and inflammatory responses, accompanied by the secretion of numerous proteins, lipids, and other mediators, incur a significant bioenergetic cost requiring the increased uptake of glucose, fatty acids, and amino acids

doi: 10.1093/jn/nxaa201

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Reduced CORT response to stress may protect breastfeeding mothers, insulating them from adverse environmental factors by reducing the response to stressful stimulation, conserving energy needed for lactation, supporting the immune system of breastfeeding women, and preventing stress-induced lactation inhibition 51

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