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While A2A receptor agonists have demonstrated efficacy in expanding Tregs and suppressing inflammation across various non-ocular models of immune-mediated diseasessuch as graft-versus-host disease (63) and in vitro systems for peripheral tolerance induction (64)their application to uveitis requires careful consideration of endpoints pertinent to ocular health

Activated JAK1 specifically phosphorylated STAT3 but not the STAT5 factor

Int J Dermatol 2016;55:1537

Wang XN, Li ZS, Ren Y, Jiang T, Wang YQ, Chen M, et al

The DSS administration reduced the abundance of Patescibacteria in both WT and EpCAM +/ mice, and the abundance of it was decreased in the EpCAM +/ group compared to WT group (Figures 5E,F)