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In silico research has shown that bilirubin can bind to the binding site of antigenic peptides of human leukocyte antigen molecules, preventing their binding to T cell receptors, which could lead to suppression of the autoimmune response ( 66 )

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Oxidized PLs (another type of DAMPs) on the membrane of ferroptotic cells could interact with TLR2 on macrophages, enhancing the phagocytic efficiency of the cells ( 2.2 Microglia As the specialized resident macrophages in the neural retina, microglia constitute a primary population of glial cells (35)