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For autoimmune patients with GI-affecting conditions, this optionality matters

In the mitochondrial matrix, moderate elevations in Ca2+ levels activate key dehydrogenases of the TCA cycle, such as isocitrate dehydrogenase (IDH) and -KG dehydrogenase (-KGDH), thereby enhancing NADH production, fueling the ETC, and increasing ATP synthase activity (88)

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(2019) 3(3):e224

Engineering Increased Vitamin C Levels in Plants by Overexpression of a D-Galacturonic Acid Reductase

Mitochondrial H 2 O 2 signaling is controlled by the concerted action of peroxiredoxin III and sulfiredoxin: linking mitochondrial function to circadian rhythm