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PLA2G4A, a member of the cytoplasmic phospholipase family, catalyzes the hydrolysis of membrane phospholipids to release AA, which produces PGE2

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The hypermethylation of specific 5-C-phosphate-G-3 (CpG) dinucleotides is detected in CpG islands previously shown to affect OXTR gene expression in ASD individuals that are correlated with aberrant oxytocinergic signaling and social interaction deficits [86]

In contrast, cholesterol derivatives negatively regulate CYP51A1 expression

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